Our Work
Work that demonstrates measurable impact
Representative examples of our work — full case studies available upon request for qualified institutional partners.
University of Colorado Anschutz Medical Campus
BRIDGE: A Behavioral Governance Layer for AI-Mediated Health Conversations
BRIDGE is a behavioral governance layer that ensures AI-mediated conversations adhere to defined behavioral intervention methodologies. It operates between the user-facing application and the underlying language model, applying explicit behavioral rules that govern how responses are structured, sequenced, and delivered.
BRIDGE does not replace the language model — it constrains and guides model behavior so that each interaction maintains fidelity to established communication frameworks such as motivational interviewing, shared decision-making, and other evidence-based behavioral support approaches. BRIDGE is the governance engine underlying CLaiRE, HDT's lung cancer survivorship AI companion, and is designed as a standalone framework applicable across behavioral health contexts.
BRIDGE Developer Kit
A self-contained deployment package for running the BRIDGE behavioral governance engine in local or controlled environments — without dependency on external prompt management services. The DK enables reproducible, auditable operation of retrieval-augmented generation, communication guardrails, simplification, crisis detection, and a four-condition experimental configuration (LLM-only, LLM+BRIDGE, RAG-only, RAG+BRIDGE). Intended for research, evaluation, and prototype development environments.
Kentucky LEADS Collaborative · University of Kentucky · University of Louisville · Lung Cancer Alliance
CLaiRE: A Digital Care Specialist Supporting Lung Cancer Survivors
RAG-powered conversational AI with animated 3D avatar supporting lung cancer survivors through symptom monitoring, psychosocial support, and shared decision-making. A multi-stage guardrails pipeline enforces empathy, non-stigmatizing language, and motivational interviewing principles throughout every interaction.
CLaiRE is designed to address a critical workforce resource gap in rural health settings — bringing evidence-based survivorship support to communities where dedicated care specialists are scarce or unavailable.
Lungevity · University of Kentucky Markey Cancer Center · Moffitt Cancer Center
Engaged LCS: Optimizing Lung Cancer Screening Delivery and Outcomes
The Engaged Approach to Lung Cancer Screening (Engaged LCS) is a framework and toolkit of materials and strategies developed through Project ACTS research, adopting a person-centered approach to lung cancer screening (LCS). The research targets adherence across each key behavioral stage: initial show/no-show rates, follow-up for identified nodules, and annual screening.
HDT supported Project ACTS through site development and hosting, providing the digital infrastructure for a multi-site research program spanning leading cancer research institutions.
University of Virginia Ryan White Clinic · Virginia Department of Health · AIDS United · M·A·C AIDS Fund
CAREiSCOPE: Chronic Health Management Through Smart Technology
CAREiSCOPE is a HIPAA-compliant, cloud-based chronic health management platform comprising a smartphone app (iOS and Android), patient dashboards, and administrative portals. The platform checks in with members daily — querying mood, stress, and medication adherence through personalized notifications, appointment reminders, and secure messaging — while giving care teams dynamic dashboards, predictive analytics, and optional EMR integration for remote care management.
CAREiSCOPE delivers significant improvement in retention in care, appointment constancy, and medication adherence across diverse patient demographics. Pilot studies in HIV management demonstrated a +119% increase in visit constancy at 12 months, +67% improvement in retention in care, +64% viral suppression, and a 17× prevention ROI — averting more than $1.8M annually per 100 members.
Origin · PositiveLinks
CAREiSCOPE originated as PositiveLinks, developed by HDT founder George Reynolds in collaboration with Rebecca Dillingham M.D., M.P.H. and Karen Ingersoll Ph.D. at the University of Virginia Ryan White Clinic, with support from AIDS United and the M·A·C AIDS Fund. A broader implementation integrating automated patient lab values and appointment data was funded by the Virginia Department of Health. PositiveLinks was so effective at the UVa Ryan White Clinic that it became a component of usual care. HDT launched it commercially as CAREiSCOPE in 2019.
